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Familial CaLS may correspond to a form of Legius syndrome, although this has been ruled out in some cases.24 Mosaic forms of NF1 may exist exclusively with cutaneous involvement and NF1 mutations may not be detectable in circulating leukocytes.19 It may even be the case that the mutation resides in another gene of the RAS pathway.33,34 McCune-Albright syndrome is characterized by extensive CaLS, often with a unilateral segmental distribution and irregular borders

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Full Body whitening injection is a non-invasive treatment, so it is a completely safe procedure